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Correlation Between Peripheral Blood Cold-Inducible RNA-Binding Protein Levels and the Severity of Lung Injury in Patients With Sepsis

Correlation Between Peripheral Blood Cold-Inducible RNA-Binding Protein Levels and the Severity of Lung Injury in Patients With Sepsis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129508
Enrollment
Unknown
Registered
2026-08-05
Start date
2026-09-26
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Mild-to-moderate lung injury group:None
No significant lung injury group:None
Severe acute lung injury group:None

Sponsors

Fuzhou University Affiliated Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients meeting the Sepsis 3.0 diagnostic criteria (SOFA score = 2 with a confirmed source of infection); 2.Age 18–80 years; 3.Admission to the ICU within 24 hours.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women; 2.Presence of malignant tumors or immunodeficiency disorders; 3.Recent treatment with immunosuppressive agents; 4.Presence of chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) or pulmonary fibrosis; 5.Any other condition deemed inappropriate for inclusion by the investigators.

Design outcomes

Primary

MeasureTime frame
Serum CIRP concentration;—

Secondary

MeasureTime frame
Murray Lung Injury Score;PaO2/FiO2;Blood lactate level;28-day mortality;Length of ICU stay;Sequential Organ Failure Assessment score;—

Countries

China

Contacts

Public ContactXiaobin Pan

Fuzhou University Affiliated Provincial Hospital

997959506@qq.com+86 591 88618701

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026