acute ST-segment elevation myocardial infarction (STEMI)
Conditions
Interventions
control group:Standard of care for STEMI
Experimental group:Standard of care for STEMI plus Shenfu injection
Sponsors
Shanghai Ninth Peoples Hospital,Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.patients with STEMI aged = 18 years and = 85 years; 2.eligible for emergency PCI and have undergone emergency coronary intervention; 3.able to understand the purpose of this study, voluntarily participate, and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Left main coronary artery disease, graft vessel disease, or acute stent thrombosis; 2. Cardiogenic shock or hemodynamic instability (requiring mechanical circulatory support); 3. Prior history of myocardial infarction or coronary artery bypass grafting; 4. Systolic blood pressure > 160 mmHg; 5. Presence of other severe comorbidities (e.g., malignancy, organ transplantation or candidates for transplantation); 6. Known allergy to Shenfu Injection; 7. Severe hepatic or renal dysfunction (ALT/AST > 3 x upper limit of normal, eGFR < 30 mL/min/1.73 m^2).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite endpoint of MACEs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events, serious adverse events;cardiac funciton;Myocardial infarct size; | — |
Countries
China
Contacts
Public ContactJun Gu
Shanghai Ninth Peoples Hospital,Shanghai JiaoTong University School of Medicine
Outcome results
None listed