Osteoporosis
Conditions
Interventions
Osteoporosis High-Risk Population Observation Group:None
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 99 years, male or female; 2. Individuals at high risk of osteoporosis, as defined by the Guidelines for the Diagnosis and Treatment of Primary Osteoporosis (2022), meeting any one of the following criteria (see Appendix 1): (1) Positive IOF 1-minute test; (2) OSTA index < -1; (3) Other risk factors for osteoporosis, such as patients with moderate-to-high fracture risk assessed by FRAX®; 3. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with acute exacerbation or decompensated phase of various chronic diseases (including heart, lung, liver, and kidney diseases) who, in the investigator's judgment, are unable to safely complete physical function tests; 2. Those who have experienced a fracture or undergone orthopedic surgery within the past 3 months; 3. Individuals with concurrent malignant tumors (life expectancy 7.5 mg/day for > 3 months) or other potent medications affecting muscle/bone metabolism; 5. Those with cognitive impairment, mental illness, or communication disorders that prevent understanding of the study content or cooperation with the assessment; 6. Individuals with limited mobility due to neurological diseases (e.g., hemiplegia, Parkinson's disease), severe osteoarthritis, or diabetic foot, rendering them unable to independently complete the 6-meter walk or sit-to-stand test; 7. Any other conditions that, in the opinion of the investigator, make the individual unsuitable for participation in this study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| muscle mass (ASMI measured by DXA), handgrip strength, and physical function (gait speed, 5-time chair stand test, SPPB);handgrip strength; physical function (gait speed, 5-time chair stand test, SPPB); | — |
Primary
| Measure | Time frame |
|---|---|
| The prevalence of sarcopenia; | — |
Countries
China
Contacts
Public ContactQixian Wang
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed