Chronic Aphasia Following a Stroke
Conditions
Interventions
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Completed preliminary clinical trials: Patients who participated in the institution-led "Study on Speech Function Improvement Following Right C7 neurotomy at the intervertebral foramen in Patients with Post-Stroke Aphasia: An Exploratory Randomized Controlled Clinical Trial."; 2. Ages 40–70; 3. Informed Consent: I, or my legal guardian, fully understand the purpose and procedures of this long-term follow-up study and voluntarily sign the informed consent form for the long-term follow-up study.
Exclusion criteria
Exclusion criteria: 1. Participants with new-onset severe neurological disorders: Since the conclusion of the previous clinical study, participants who have experienced a new-onset severe traumatic brain injury, a new-onset stroke (ischemic or hemorrhagic), or have been diagnosed with other neurodegenerative diseases (such as Parkinson’s disease, Alzheimer’s disease, etc.), and who, in the investigator’s assessment, are likely to significantly interfere with the results of this language function assessment; 2. Severe, uncontrolled systemic diseases: Participants with severe systemic diseases (such as heart failure, respiratory failure, renal failure, or malignant tumors) or those in extremely poor general condition for any reason, whom the investigator determines are unable to complete the follow-up assessment procedures; 3. New or Changed Contraindications for MRI: The presence or new implantation of any items or conditions contraindicated for magnetic resonance imaging (MRI) (such as a new type of incompatible pacemaker or aneurysm clip implanted in the body, or the onset of claustrophobia), resulting in the inability to complete the neuroimaging examination; 4. Death, voluntary withdrawal, or loss to follow-up: Study participants who die from the disease; who explicitly withdraw their informed consent and request to withdraw from the study; or who cannot be contacted through various means (telephone, mail, home visits, etc.), resulting in the inability to complete follow-up data collection.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| fugl-meyer assessment;Range of Motion;Two-Point Discrimination and Tactile Thresholds;Upper Limb Muscle Strength;Western Aphasia Battery (WAB) Mandarin Version;Functional Magnetic Resonance Imaging Scan; | — |
Primary
| Measure | Time frame |
|---|---|
| Boston Naming Test (BNT); | — |
Countries
China
Contacts
Public ContactXu Wendong
Huashan Hospital, Fudan University
Outcome results
None listed