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A Pilot Study and Mechanistic Investigation of a Novel Weaning Assessment Trial for Patients on VA-ECMO

A Pilot Study and Mechanistic Investigation of a Novel Weaning Assessment Trial for Patients on VA-ECMO

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600129472
Enrollment
Unknown
Registered
2026-08-05
Start date
2026-08-05
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiogenic shock, cardiac arrest

Interventions

Test Group 1:First, a new type of ECMO removal assessment test was conducted. After a washout period of 0.5 to 1 hour, the ECMO blood flow and gas flow rate were adjusted to the parameters used in the
Test Group 2:First, a traditional ECMO weaning assessment trial was conducted. After a washout period of 0.5 to 1 hour, the ECMO blood flow and gas flow rate were adjusted to the parameters used in th

Sponsors

The First Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=18 years old; 2.Patients receiving VA-ECMO treatment; 3.Peripheral femoral artery and femoral vein catheterization; 4.During this hospitalization, VA ECMO support was received for the first time

Exclusion criteria

Exclusion criteria: 1.Pulmonary embolism; 2.VA ECMO or VAV mode of central catheterization; 3.Patients expected to die within 36 hours after ECMO support; 4.Patients who cannot undergo weaning tests; 5.Patients who have received VA ECMO support for the second or more times; 6.Patients with missing clinical data or difficult follow-up

Design outcomes

Primary

MeasureTime frame
Weaning outcome of the patient;

Secondary

MeasureTime frame
Minute ventilation;Heart rate;Blood pressure;Partial pressure of carbon dioxide;Heart rate;Blood gas analysis;Hospitalization outcome;

Countries

China

Contacts

Public ContactXu Yonghao

The First Affiliated Hospital of Guangzhou Medical University

dryonghao@163.com+86 20 83062114

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026