primary colorectal adenocarcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Pathologically confirmed primary colorectal adenocarcinoma; 2. Received neoadjuvant therapy (including chemoradiotherapy and/or immunotherapy) followed by radical surgery; 3. Had complete clinicopathological data and documented therapeutic response evaluation records; 4. Had intact and available paraffin-embedded tumor tissue specimens.
Exclusion criteria
Exclusion criteria: 1. Had a prior history of other malignancies; 2. Received unplanned preoperative therapy; 3. Had postoperative pathological confirmation of residual lesions that precluded efficacy evaluation; 4. Had specimens of inadequate quality (e.g., severe autolysis or excessive necrotic area).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tumor regression; | — |
Secondary
| Measure | Time frame |
|---|---|
| HE4/WFDC2 protein expression level; | — |
Countries
China
Contacts
The First Affiliated Hospital of Shantou University Medical College