Cardio-psychological disorders
Conditions
Interventions
Control group:Routine care (psychological support + exercise education + symptomatic medication)
Intervention group 2:Portable ECG monitoring + active alerting + internet-based medical support + home-based ABC slow rehabilitation three-exercise training (diaphragmatic breathing, standing postures
Intervention group 1:Portable ECG monitoring + active alerting + internet-based medical support
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18 to 65 years (inclusive); 2.Core symptoms: chief complaint of recurrent (=1 month) cardiac-related symptoms such as palpitations, chest tightness, chest pain, or shortness of breath, with cardiovascular physician ruling out organic heart disease; 3.GAD-7 = 3 or PHQ-9 = 3, and PHQ-15 = 5; 4.Able to understand and voluntarily sign written informed consent;
Exclusion criteria
Exclusion criteria: 1.Definite diagnosis of unstable angina, acute myocardial infarction, or heart failure (NYHA class III or IV); 2.Severe structural heart disease (e.g., moderate-to-severe valvular heart disease, hypertrophic obstructive cardiomyopathy, left ventricular ejection fraction < 50%); 3.Arrhythmias requiring treatment (e.g., persistent or permanent atrial fibrillation, sick sinus syndrome, untreated second-degree type II or higher atrioventricular block); 4.Any unforeseen, clinically significant arrhythmia or myocardial ischemia requiring intervention detected during the 1-week monitoring perio; 5.Uncontrolled hyperthyroidism, severe anemia (hemoglobin < 80 g/L), acute exacerbation of chronic obstructive pulmonary disease, or severe hepatic/renal insufficiency; 6.Severe psychiatric disorders such as schizophrenia, bipolar disorder, substance abuse or dependence, severe anxiety/depression, or current severe suicidal ideation or behavior; 7.Pregnant or breastfeeding women; 8.Inability to use smartphone applications proficiently, or presence of hearing/cognitive impairments affecting study communication and data collection; 9.Concurrent participation in other clinical trials that may interfere with the results of this study; 10.Any other condition judged by the investigator to place the subject at high risk or interfere with study completion;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Somatic symptom score (PHQ-15); | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression symptom score (PHQ-9);Anxiety symptom score (GAD-7);Cardiac autonomic reflex tests (CARTs) score;Quality of life score (SF-12);Heart rate variability (HRV); | — |
Countries
China
Contacts
Public ContactDing Rongjing
Peking Union Medical College Hospital
Outcome results
None listed