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Study on the regulatory role and mechanism of MAPK15 in intestinal epithelial cell senescence in inflammatory bowel disease (IBD)

Study on the regulatory role and mechanism of MAPK15 in intestinal epithelial cell senescence in inflammatory bowel disease (IBD)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129373
Enrollment
Unknown
Registered
2026-08-04
Start date
2025-01-15
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory bowel diseases

Interventions

healthy control group:None
UC group:None

Sponsors

Hunan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Colonic mucosal biopsy samples were collected from UC patients and non-UC healthy donors in the Gastroenterology Department based on endoscopic findings. The diagnosis of UC was established through comprehensive clinical, radiological, endoscopic, and histopathological evaluations.

Exclusion criteria

Exclusion criteria: 1. History of total colectomy within 3 months before or after the scheduled colonoscopy during the predefined study period; 2.Presence of advanced colorectal neoplasia (defined as high-grade dysplasia [HGD] and/or colorectal cancer [CRC]) at the time of or prior to colonoscopy.

Design outcomes

Primary

MeasureTime frame
mitogen-activated protein kinase 15;—

Countries

China

Contacts

Public ContactLi Juan

Hunan Provincial People's Hospital

ljhao85@163.com+86 731 84762699

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026