Perihilar cholangiocarcinoma
Conditions
Interventions
Negative clamp test group & Positive clamp test group:None
Sponsors
Beijing Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years, male or female, ECOG performance status score of 0–1, Child-Pugh class A or B; 2.Diagnosis of hilar cholangiocarcinoma confirmed by pathology, cytology, or by imaging findings combined with clinical data; 3.Received PTCD for malignant obstructive jaundice; 4.Received HAIC after PTCD, with the specific regimen based on real-world clinical treatment records at the study center; 5.Rchieved jaundice relief after treatment and underwent a clamp test according to clinical evaluation; 6.Clamp test-related data and follow-up information were complete or substantially complete;
Exclusion criteria
Exclusion criteria: 1.History of biliary stent placement or biliary stent placement shortly after PTCD combined with HAIC; 2.Previous diagnosis of any other malignancy, except basal cell carcinoma or squamous cell carcinoma of the skin treated with curative intent, or cervical carcinoma in situ; 3.No actual clamp test performed or clamp test results unavailable for evaluation; 4.Missing key outcome data, such as survival status, date of last follow-up, or records of biliary reintervention; 5.Any other conditions deemed unsuitable for inclusion in the analysis by the investigators.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Duration of jaundice relief;Adverse events related to clamping and tube removal;The rate of no drainage and no jaundice for 6/12/24 months;overall survival;Rate of clamping;Jaundice-free and drainage-free duration;Rate of biliary re-intervention; | — |
Primary
| Measure | Time frame |
|---|---|
| Negative rate of the clamping test;Rate of tube removal; | — |
Countries
China
Contacts
Public ContactXiaodong Wang
Beijing Cancer Hospital
Outcome results
None listed