Deep sternal wound infection
Conditions
Interventions
Group C:Using cipepofol for anesthesia induction and maintenance
Group P:Using propofol for anesthesia induction and maintenance
Sponsors
Beijing Aerospace General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Voluntarily participate in this study and sign the informed consent form; (2) Patients who have undergone coronary artery bypass surgery within the past 6 months and are planning to undergo thoracoplasty; (3) American Society of Anesthesiologists (ASA) classification level II to III; (4) Left ventricular ejection fraction (LVEF) >= 45%; (5) Age 18 years or older and 75 years or younger; (6) BMI 18 to 30 kg/m2
Exclusion criteria
Exclusion criteria: (1) Have a history of allergy or contraindication to anesthetic drugs (including those in the excipients of propofol or etomidate injection: such as soybean oil, glycerin, egg yolk lecithin, etc.);(2) Have other important organ dysfunction (such as liver, kidney, respiratory, blood, nervous, immune or metabolic systems);(3) Need vasoactive drugs to maintain hemodynamic stability before the operation;(4) Have severe arrhythmia (such as second-degree or above atrioventricular conduction block, ventricular tachycardia, etc.);(5) Pregnant, lactating or planning to have a baby within the next six months;(6) Have long-term use of psychotropic drugs or glucocorticoids before the operation;(7) Have a severely difficult airway;(8) Have moderate to severe cognitive dysfunction;(9) Need to use diuretics for treatment before the operation;(10) Patients considered by the researchers to have any other factors that are not suitable for participating in this experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AUC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators;Dosage of vasoactive drugs;Quality of awakening;Cardiac injury markers;Adverse Reactions; | — |
Countries
China
Contacts
Public ContactXiong Tian
Beijing Aerospace General Hospital
Outcome results
None listed