Arrhythmia
Conditions
Interventions
Sub-study 2-Group 2 (Control):None
Sub-study 2-Group 1 (Disease exposure):None
Sub-study 1 (Testing the pacing electrode threshold during the pacemaker implantation procedure.):None
Sponsors
Shanghai Chest Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Substudy 1: (1) Patients with an indication for cardiac pacemaker implantation who are scheduled to receive the procedure, in accordance with the 2021 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy; (2) Aged between 18 and 70 years old, with no gender restriction; (3) Capable of cooperating to complete combined resting-state/task-state electroencephalography-electrocardiography recordings; (4) Voluntarily sign the informed consent form with full understanding of the study procedures. 2. Substudy 2: (1) Patients admitted to hospital due to arrhythmia; (2) Aged between 18 and 70 years old, with no gender restriction; (3) Capable of cooperating to complete combined resting-state/task-state electroencephalography-electrocardiography recordings; (4) Voluntarily sign the informed consent form with full understanding of the study procedures.
Exclusion criteria
Exclusion criteria: 1. Substudy 1: (1) Combined with severe organic heart disease, end-stage renal disease or advanced tumors; (2) Diagnosed with neurological diseases such as epilepsy, stroke sequelae, dementia and tumors, or mental illnesses such as severe depression and schizophrenia; (3) Used drugs that significantly affect electroencephalographic activities within the past month; (4) Already implanted with a brain pacemaker; (5) Already enrolled in other clinical studies that may interfere with the purpose of this study. 2. Substudy 2: (1) Combined with severe organic heart disease, end-stage renal disease or advanced malignancies; (2) Diagnosed with neurological disorders including epilepsy, stroke sequelae and dementia, or psychiatric disorders such as major depressive disorder and schizophrenia; (3) Took medications that significantly affect brain activity within the past month; (4) Already implanted with a cardiac pacemaker or brain pacemaker; (5) Already enrolled in other clinical trials that may interfere with the objectives of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cerebral function indicators;ECG;rating scale; | — |
Countries
China
Contacts
Public ContactHou Xumin
Shanghai Chest Hospital
Outcome results
None listed