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Impact of Mental Health on Clinical Outcomes of Conversion Therapy in Patients with Hepatocellular Carcinoma

Impact of Mental Health on Clinical Outcomes of Conversion Therapy in Patients with Hepatocellular Carcinoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129323
Enrollment
Unknown
Registered
2026-08-03
Start date
2026-08-11
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Triple therapy group:None
Binary therapy group:None

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Ages 18-75, male or female; 2. Patients who have been enrolled in the clinical research cohort (a randomized controlled study of HAIC combined with carlimlimab and apatinib for conversion therapy in patients with potentially resectable hepatocellular carcinoma, protocol number: MA-HCC-II/III-026); 3. They had basic cognitive function and could understand the content of psychological assessment questionnaire;

Exclusion criteria

Exclusion criteria: 1. There are serious heart, lung, kidney and other important organ dysfunction or hepatic encephalopathy, intractable ascites and other late complications; 2. Comorbid psychiatric or neurological diseases, such as major depression, schizophrenia, epilepsy, alcohol abuse, drug abuse, cognitive dysfunction, etc; 3. Pregnant women, lactating women, or those who have family planning plans but refuse to take effective contraceptive measures; 4. Other intervention psychotherapy, antipsychotic intervention, and other treatments that may interfere with the evaluation were received during the study; 5. The researchers identified other cases that were not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Overall Survival;Surgical conversion success rate;Mental Health;

Secondary

MeasureTime frame
Laboratory indicators;Quality of life;

Countries

China

Contacts

Public ContactWu Xiaojun

Zhongshan Hospital, Fudan University

wu.xiaojun@zs-hospital.sh.cn+86 21 64041990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026