Multiple system atrophy
Conditions
Interventions
Gold Standard:Clinically established multiple system atrophy (MSA) according to the International Parkinson and Movement Disorder Society (MDS) clinical diagnostic criteria for MSA (2022) and the Chin
Index test:Neurological Disease Multiple System Atrophy (MSA) Diagnosis and Treatment Model
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
30 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Retrospective inclusion criteria: (1) Age 30 years and older; (2) Hospitalized patients with clinically established or clinically probable multiple system atrophy (MSA); (3) Patients meeting the criteria for clinically established MSA according to the International Parkinson and Movement Disorder Society clinical diagnostic criteria for multiple system atrophy (2022) and the Chinese Expert Consensus on Diagnostic Criteria for Multiple System Atrophy (2022). 2.Prospective inclusion criteria: (1) Age 30 years and older; (2) Hospitalized patients with clinically established or clinically probable multiple system atrophy (MSA); (3) Patients meeting the criteria for clinically established MSA according to the International Parkinson and Movement Disorder Society (MDS) clinical diagnostic criteria for multiple system atrophy (2022) and the Chinese Expert Consensus on Diagnostic Criteria for Multiple System Atrophy (2022); (4) Patient or legal guardian able to understand the study content and provide informed consent; (5) Clinically stable condition and able to comply with the study procedures.
Exclusion criteria
Exclusion criteria: 1.Retrospective exclusion criteria: (1) Medical records altered or obliterated, rendering information unreadable or uninterpretable; (2) Examination reports smudged, obliterated, or damaged, making recognition by the large model difficult or impossible; (3) Patients with comorbid severe psychiatric disorders (e.g., depression, mania, epileptic seizures, schizophrenia, etc.); (4) Cases with severe missing or incomplete clinical information. 2.Prospective exclusion criteria: (1) Patients with comorbid severe psychiatric disorders (e.g., depression, mania, epileptic seizures, schizophrenia, etc.); (2) Patients deemed by the investigator unable to cooperate with or complete the study procedures; (3) Patients with strong accent or poor audio recording quality that prevents accurate information extraction or recognition; (4) Examination reports smudged, obliterated, or damaged, rendering recognition by the large model difficult or impossible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage score for each case's diagnostic and treatment task (range: 0–100 points); | — |
Secondary
| Measure | Time frame |
|---|---|
| 85% accuracy on the MSA medical record generation task;Physician subjective satisfaction score with system use (range: 0–100 points); | — |
Countries
China
Contacts
Public ContactDingYan
Xuanwu Hospital Capital Medical University
Outcome results
None listed