Autoimmune encephalitis (AIE)
Conditions
Interventions
cohort of patients with suspected AIE:NA
cohort of patients with confirmed AIE:NA
Sponsors
Punan Hospital, Pudong New Area, Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, both genders. 2. Attending the neurology department of one of the three collaborating hospitals and meeting the diagnostic criteria for suspected or confirmed autoimmune encephalitis (AIE). 3. Patients with confirmed AIE must have completed routine imaging examinations and immunological tests, with complete data, and be able to cooperate with short-term efficacy evaluation and long-term follow-up. 4. Voluntarily participate in this study and sign the informed consent form. 5. For patients in the retrospective cohort, informed consent is supplemented by their family members or legally authorized representatives (if applicable).
Exclusion criteria
Exclusion criteria: 1. Subjects unwilling to participate in the clinical study. 2. Combined severe dysfunction of vital organs such as the heart, liver, kidneys, or lungs, making it impossible to complete the relevant examinations and follow-up. 3. Combined with other autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis, etc.) that may affect the study results. 4. Pregnant or breastfeeding women. 5. Patients with psychiatric disorders who are unable to cooperate with data collection and assessment. 6. Incomplete data that cannot be included in the statistical analysis. 7. Patients who have not completed the main diagnosis, treatment, and examination processes at the above-mentioned three collaborating hospitals, and thus cannot provide complete study data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The core predictive indicators and cutoff values of the sample submission decision-making model; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale;Collect the treatment plans, treatment responses and follow-up data of patients diagnosed with AIE, and record the NEOS score and NEOS2 score;radiologic characteristic;Immunology data; | — |
Countries
China
Contacts
Public ContactWang Kan, Guan Yangtai
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed