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Molecular typing of intestinal metaplasia and identification of high-risk intestinal metaplasia

A Study on the Molecular Subtyping of Intestinal Metaplasia of the Gastric Mucosa and the Identification of High-Risk Intestinal Metaplasia of the Gastric Mucosa

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129263
Enrollment
Unknown
Registered
2026-08-03
Start date
2026-08-03
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intestinal metaplasia of gastric mucosa

Interventions

Sponsors

The Second Affiliated Hospital of the Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age >= 40 years old, <= 80 years old, gender not limited; 2.Previous gastroscopy revealed the presence of chronic atrophic gastritis or intestinal metaplasia;

Exclusion criteria

Exclusion criteria: 1.Previous gastroscopy results indicated significant bile reflux; 2.After evaluation, it is considered that the risk of adverse events during gastroscopy and biopsy is relatively high; 3.Previous history of gastric surgery; 4.History of malignant tumor in the digestive tract; 5.History of hereditary gastrointestinal diseases; 6.Autoimmune gastritis; 7.Severe systemic disease; 8.Received eradication treatment for Helicobacter pylori or other antibiotic treatments within the past 3 months; 9.Used proton pump inhibitors (PPIs) and H2 receptor antagonists within the past month; 10.Used non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin within the past month;

Design outcomes

Primary

MeasureTime frame
Expression of molecular markers associated with high-risk intestinal metaplasia;

Countries

China

Contacts

Public ContactHu Changjiang

The Second Affiliated Hospital of the Army Medical University

hcj888@tmmu.edu.cn+86 23 68774195

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026