Lumbar spondylolisthesis
Conditions
Interventions
Control group ( group D ):On the basis of conventional anesthesia induction and maintenance, the control group was given the same dose of normal saline instead of esketamine for injection.
Esketamine group ( group A ):On the basis of conventional anesthesia induction and maintenance, patients in the esketamine group were additionally given a 0.2 mg/kg intravenous injection of esketamine
Sponsors
The First Affiliated Hospital of Guilin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.ASA grade I-III; 3.Spinal surgery under general anesthesia; 4.To correctly understand the relevant assessment scale of this study.
Exclusion criteria
Exclusion criteria: 1.To study the history of drug allergy; 2. Patients with mental illness or preoperative use of psychotropic drugs; 3. patients with severe heart, lung, liver and kidney dysfunction; 4. Those with a serious risk of elevated blood pressure or intracranial pressure; 5. Patients with poorly controlled or untreated hypertension (resting systolic / diastolic blood pressure > 180 / 100mmHg); 6. pregnant women and lactating women; 7. untreated or inadequately treated hyperthyroidism; 8. Emergency surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative quality of recovery scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score;Hospital anxiety and depression rating scale;Safety indicators: Adverse events (AE), serious adverse events (SAE), abnormal laboratory tests, intervention-related complications.; | — |
Countries
China
Contacts
Public ContactQin Chaosheng
The First Affiliated Hospital of Guilin Medical University
Outcome results
None listed