Patients with acute-on-chronic liver failure who received artificial liver treatment for the first time
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.presence of chronic hepatitis B virus infection, meeting the diagnostic criteria for acute-on-chronic liver failure (ACLF), and receiving artificial liver treatment for the first time due to this condition; 3.the artificial liver treatment mode is DPMAS + PE, and the treatment period is between January 1, 2018 and December 31, 2025.
Exclusion criteria
Exclusion criteria: 1. History of malignancy or suspected malignancy; 2. Plan to receive a non-liver organ transplant or have performed any organ transplant; 3. Maternal, mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality within 90 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| The dynamic trajectory of the patient's condition changes;The 90-day mortality rate with liver transplantation as the competing event;90-day survival rate without transplantation; | — |
Countries
China
Contacts
West China Hospital of Sichuan University