Patients who underwent combined thoraco-abdominal laparoscopic radical resection for esophageal tumors
Conditions
Interventions
R group:Control group: Ropivacaine Hydrochloride Injection
L group:Experimental group: Liposomal Bupivacaine Injection
Sponsors
HenanCancerHospital
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 45 - 75 years old; 2.no gender limitation; 3.American Society of Anesthesiologists (ASA) Physical Status Classification System Grade ? to ?; 4.Body mass index (BMI) 18.5 to 30.0 kg/m²; 5.Patients undergoing radical resection of esophageal cancer under general anesthesia via combined thoracoscopic and laparoscopic approach;
Exclusion criteria
Exclusion criteria: 1.Patients with a long history of chronic pain or opioid dependence preoperatively. 2.Patients with a history of allergy to local anesthetics or opioids. 3.Patients with contraindications to regional nerve blocks. 4.Patients who cannot cooperate with the study assessments due to cognitive or communication disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Recovery Quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of cases with postoperative rescue analgesia and the amount of rescue analgesic medication used;Postoperative adverse reactions and complications;Time to first ambulation and time to first flatus;Rest and activity NRS scores at 2, 12, 24, 48, and 72 hours postoperatively;Postoperative Sufentanil Consumption; | — |
Countries
China
Contacts
Public ContactLu Xihua
HenanCancerHospital
Outcome results
None listed