Hip fracture in the elderly
Conditions
Interventions
Trial group:For the patients in the experimental group, 1 mg of tegretol was administered intravenously as the loading dose, which was infused within 10 minutes. It was combined with PCIA, with a conc
Control group:For the control group patients, sufentanil 0.1 µg/kg was added at the end of the surgery, combined with PCIA, with a sufentanil concentration of 2 µg/ml, totaling 100 ml. The background
Sponsors
Department of Anesthesiology, Sinopharm Gezhouba Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.ASA grade II-III; 2. for patients over 65 years old who plan to undergo hip fracture surgery under general anesthesia, either artificial femoral head replacement or anti-rotation intramedullary nails can be used as surgical methods.
Exclusion criteria
Exclusion criteria: 1.ASA grade III or above; 2.emergency patients; 3.New York Heart Function Classification (NYHA) grade 3-4; 4.cardiac conduction block (sinus node conduction block or atrioventricular conduction block); 5.gastric ulcer; 6.body mass index (BMI) > 37 kg/m2; 7. patients with poorly controlled diabetes treated with insulin; 8.kidney diseases; 9.liver diseases; 10.patients with blood clotting disorders or those taking warfarin, new anticoagulants such as rivaroxaban or dabigatran due to other disease reasons; 11.patients who have engaged in heavy drinking or have severe dependence on narcotic and psychotropic drugs in the past two months; 12.patients with uncontrollable anxiety, schizophrenia or other mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the pain score curve at 48 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of PCA iterations;Recovery of analgesic effect frequency within 0–48 hours;IL-6;IL-8;First PCA time; | — |
Countries
China
Contacts
Public ContactZhan Weiwei
Sinopharm Gezhouba Central Hospital
Outcome results
None listed