Adult patients undergoing clinically indicated 3.0-T contrast-enhanced head and neck MRI for diseases involving the nasopharynx, oropharynx, hypopharynx, larynx, salivary glands, thyroid gland, cervical soft tissues, or cervical lymph nodes, without restriction to a single disease.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years, both genders. 2. In need of contrast-enhanced 3.0T head and neck MRI for clinical diagnosis or treatment, with examination sites including but not limited to the nasopharynx, oropharynx, hypopharynx, larynx, salivary glands, thyroid, cervical soft tissues, or cervical lymph nodes. 3. Alert and able to understand and cooperate with basic examination instructions. 4. Planned to undergo the routine departmental contrast-enhanced head and neck MRI protocol. 5. Voluntarily agrees to participate in the study and signs the written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Presence of contraindications to MRI, such as metal implants that do not meet MRI safety requirements, cardiac pacemakers, or other implanted devices. 2. Presence of contraindications to gadolinium-based contrast-enhanced examination, or a prior history of severe allergic reaction to gadolinium-based contrast agents. 3. Pregnant or breastfeeding women. For women of childbearing potential, the possibility of pregnancy will be assessed according to routine clinical practice; if pregnancy is possible and cannot be ruled out, the subject will not be included in this study. 4. Severe renal insufficiency or other conditions judged by the clinician to make the subject unsuitable for gadolinium-based contrast-enhanced examination. 5. Severe claustrophobia preventing completion of the MRI examination. 6. Severe cognitive impairment, psychiatric or behavioral abnormalities, or hearing impairment that prevent understanding and cooperation with examination instructions. 7. Severe dysphagia, significant risk of aspiration, frequent coughing, or oropharyngeal conditions that make the use of a bite block or gauze rolls unsuitable. 8. Inability to bite normally due to prior oral or pharyngeal surgery or trauma, or if bite training may cause significant discomfort. 9. Cervical spine fixation or immobilization preventing supine positioning, requiring general anesthesia or deep sedation to complete the examination. 10. Refusal to participate in the study, or other conditions deemed by the investigator to make the subject unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical diagnostic acceptability rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall image quality score;Quality scores of each sequence image;The key anatomical structures show quality scores;The severity of motion artifacts related to swallowing;Diagnostic confidence score;Scanning efficiency index; | — |
Countries
China
Contacts
Beijing Friendship Hospital ,Capital Medical University