Dry mouth after a major surgery under general anesthesia
Conditions
Interventions
Control group:Moisten the mouth with 2 ml of normal saline. Use a clean cotton swab to moisten the inner walls of the patient's mouth and the upper and lower lips. Repeat this process three times to e
Oral Restoration Solution Group:Apply 2 ml of the repair solution to the mouth. Use a clean cotton swab to moisten the inner and outer walls of the patient's mouth as well as the upper and lower lips.
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-75; 2.ASA classification I-III; 3.Elective major surgery under general anesthesia (surgery duration >=2 hours);
Exclusion criteria
Exclusion criteria: 1.Had dry mouth symptoms before surgery (Schirmer test <5mm/5min) or Sjogren's syndrome; 2.Active oral ulcers or fungal infections; 3.Long-term use of drugs that cause dry mouth, like anticholinergics or antidepressants; 4.Refusal to use oral moisturizing solutions; 5.Patient has cognitive impairment or other mental health issues;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Highest xerostomia score at 6 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery at 24 hours postoperatively (QoR15);Incidence of postoperative nausea and vomiting (PONV);Thirst and xerostomia scores at 30 min, 1 h, 2 h, and 6 h postoperatively; | — |
Countries
China
Contacts
Public ContactPeng Ke
The First Affiliated Hospital of Soochow University
Outcome results
None listed