Post-Stroke Motor Dysfunction
Conditions
Interventions
tTIS-VIM Group:Transcranial Temporal Interference Stimulation (tTIS) targeting the ventral intermediate nucleus of the thalamus
tTIS-M1 Group:Transcranial Temporal Interference Stimulation (tTIS) targeting the primary motor cortex
Sponsors
Jiangsu Provincie Official Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–75 years old, any gender; 2. First-ever stroke confirmed by imaging as basal ganglia stroke; 3. Disease course >=6 months and <=2 years; 4. Fugl-Meyer Upper Extremity Score <=47 points; 5. The patient or immediate family member is capable and willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe cardiac, pulmonary, hepatic or renal insufficiency; 2. Limb dysfunction secondary to other diseases (e.g., joint contracture); 3. Contraindications to tTIS treatment or MRI scans (e.g., intracranial metal implants, large skull defects, cardiac pacemakers; ventricular shunts are permitted for enrollment); 4. Recent grand mal epileptic seizures; 5. Poor compliance, unable to complete assessments and treatment; 6. Currently participating in another clinical trial, or enrolled in another clinical trial within 3 months prior to screening; 7. Other conditions deemed unsuitable for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Upper Extremity Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Upper Extremity Scale;Wolf Motor Function Test;Modified Ashworth Scale;Hand Function Assessment;Incidence and severity of adverse events; | — |
Countries
China
Contacts
Public ContactLixia Zhang
Jiangsu Provincie Official Hospital
Outcome results
None listed