Hepatocellular carcinoma
Conditions
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 80 years; 2.Patients diagnosed with initially unresectable hepatocellular carcinoma (uHCC) who received conversion therapy, including but not limited to oral or intravenous chemotherapy, transarterial chemoembolization (TACE), radiofrequency ablation (RFA), and yttrium-90 selective internal radiation therapy (Y-90 SIRT). 3.Evidence of tumor shrinkage and downstaging on preoperative imaging after conversion therapy. 4.Undergone hepatic resection. 5.Completed preoperative assessment and three-dimensional reconstruction, with estimated future liver remnant volume meeting the criteria for anatomical liver resection. 6.Complete clinical data available.
Exclusion criteria
Exclusion criteria: 1.Failure to meet the above inclusion criteria. 2.Severe cardiac, hepatic, or renal insufficiency, or severe malnutrition not correctable by medical therapy. 3.Tumor with complete invasion or encasement of major vessels, or presence of tumor thrombus. 4.Evidence of intra-abdominal or distant metastasis. 5.Pregnancy, lactation, or planned pregnancy in women of childbearing age. 6.Other conditions deemed unsuitable for enrollment by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival and Recurrence Endpoints; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative Complications;Intraoperative Variables; | — |
Countries
China
Contacts
Public ContactShuguo Zheng
The First Affiliated Hospital of Army Medical University
Outcome results
None listed