Sepsis
Conditions
Interventions
Low Inflammatory Phenotype Group:None
High Inflammatory Phenotype Group:None
Sponsors
Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age > 18 years. 2. First time in the ICU. 3. Expected survival time >= 24 hours.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women. 2. Patients who underwent CPR during this hospital stay. 3. Those with clear causes of central nervous system diseases, including: acute cerebrovascular disease (e.g., hemiplegia, cranial nerve palsy); central nervous system infection (e.g., increased cerebrospinal fluid cell count); organ-related encephalopathy (e.g., hepatic, renal, pulmonary, or pancreatic encephalopathy); drug-related encephalopathy (e.g., antipsychotics, serotonin syndrome, antibiotics); other encephalopathies (head trauma, intracranial tumors, immune-related encephalopathy, metabolic encephalopathy, etc.). 4. Patients unable to cooperate with EEG monitoring (e.g., scalp injury/infection).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantified Electroencephalographic features and Young Classification Grade;Favorable Neurological Prognosis Rate (CPC Score); | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality;Length of ICU Stay;Montreal Cognitive Assessment (MoCA) Score;Health-Related Quality of Life (EQ-5D-5L Index); | — |
Countries
China
Contacts
Public ContactLina Zhang
Xiangya Hospital of Central South University
Outcome results
None listed