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Pain Trajectories, Opioid Analgesic Response, and Associated Biomarkers: A Real-World Cohort Study in Cancer-Related Pain Patients

Pain Trajectories, Opioid Analgesic Response, and Associated Biomarkers: A Real-World Cohort Study in Cancer-Related Pain Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129170
Enrollment
Unknown
Registered
2026-07-31
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer related pain

Interventions

Moderate-to-Severe Cancer Pain Group:None
Mild Cancer Pain Group:None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Malignant tumor confirmed by pathological, cytological, imaging, or clinical diagnosis; 3. Presence of cancer-related pain, including pain caused by the tumor itself, metastases, anti-tumor therapy, or tumor-related complications; Numerical Rating Scale (NRS) score >=1, or currently receiving analgesic therapy.

Exclusion criteria

Exclusion criteria: 1.Patients whose primary source of pain is clearly identified as non-cancer-related conditions; 2.Patients with severely missing clinical data, such that pain status or primary outcomes cannot be assessed; 3.Patients with severe cognitive impairment, mental disorders, or communication difficulties who do not have a reliable caregiver to assist in completing the assessments;

Design outcomes

Primary

MeasureTime frame
Pain intensity;

Secondary

MeasureTime frame
Quality of life;Opioid treatment response rate;Functional status;Average daily opioid equivalent dose;

Countries

China

Contacts

Public ContactBixin Zheng

West China Hospital of Sichuan University

binxin.zheng@scu.edu.cn+86 28 85422337

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026