Early esophageal cancer and precancerous lesions
Conditions
Interventions
Gold Standard:Taking the pathological test results as the gold standard
Index test:Experimental group (domestic endoscope group): Utilized domestic Keli ultra-resolution imaging technology combined with 4K imaging for the endoscope: Gastroscopy model: EG650, EG650T. Contr
Sponsors
Beijing Friendship Hospital ,Capital Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 40–75 years old; 2. Patients receiving endoscopic examination due to gastrointestinal symptoms (e.g., retrosternal discomfort, burning sensation, foreign body sensation during swallowing, etc.) or screening (e.g., endoscopic examination for high-risk populations); 3. Suspected lesions are identified endoscopically, and patients agree to undergo targeted biopsy; 4. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of esophageal surgery; 2. Advanced malignant tumors of the esophagus; 3. Previous radiotherapy or chemotherapy; 4. Poor image quality (e.g., massive mucus or air bubbles obscuring the view, making the mucosal surface unable to be clearly visualized); 5. Patients with contraindications to endoscopy or anesthesia, including those taking anticoagulants or antiplatelet agents or with contraindications to biopsy; 6. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity and specificity for the diagnosis of early esophageal cancer and precancerous lesions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Using pathology as the gold standard, compare the differences in the diagnosis of the nature and boundary judgment of early esophageal cancer and precancerous lesions between the two imaging techniques (sensitivity, specificity, positive predictive value, negative predictive value).; | — |
Countries
China
Contacts
Public ContactLi Peng
Beijing Friendship Hospital ,Capital Medical University
Outcome results
None listed