Congenital cleft lip and palate
Conditions
Interventions
Case group (non-syndromic cleft lip and palate children):None
Control group (children without congenital malformations):None
Sponsors
QingHai University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 5 Years
Inclusion criteria
Inclusion criteria: 1. Live-born neonates or infants under 5 years old who have been clearly diagnosed with congenital cleft lip and palate by clinicians; 2. The mothers of the children are informed of the research and have given their consent to participate.
Exclusion criteria
Exclusion criteria: 1. Diagnosed with syndromic cleft lip and palate (e.g., associated with Van der Woude syndrome, etc.), because these cases usually have a clear monogenic genetic background that may interfere with the analysis of multifactorial causes; 2. Mothers with severe mental illness or communication disorders who are unable to complete the questionnaire; 3. Children who are adopted or whose maternal information is incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of congenital cleft lip and palate and related risk factors; | — |
Secondary
| Measure | Time frame |
|---|---|
| Different types of cleft lip and palate in pediatric patients; | — |
Countries
China
Contacts
Public ContactLi Shengmei
QingHai University Affiliated Hospital
Outcome results
None listed