Osteoporosis
Conditions
Interventions
Gold Standard:The diagnosis of osteoporosis was based on the DXA-based diagnostic criteria established by the World Health Organization (WHO) in 1994.
Index test:DeepBMD model (an AI screening model for osteoporosis based on non-contrast CT).
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Study Group 1: (1) Underwent a plain chest CT scan using the hospital’s Philips IQon spectral CT scanner, with images of acceptable quality and free from severe artefacts; (2) Identified by the DeepBMD model as a high-risk individual for osteoporosis screening; (3) Valid contact details are recorded in the PACS system; the patient is cognitively sound and able to cooperate with telephone follow-ups and on-site examinations; (4) The patient voluntarily participates in the study, is able to sign a written informed consent form on site, and agrees to undergo DXA testing. Study Group 2: Patients who underwent plain chest and abdominal CT scans and DXA examinations at our hospital during the same period from April to June 2026.
Exclusion criteria
Exclusion criteria: 1. Severe spinal deformity, postoperative spinal internal fixation, malignant bone metastasis, or severe osteolytic lesions that may interfere with measurements; 2. A confirmed diagnosis of osteoporosis with ongoing standardized treatment; 3.Inability to be contacted, explicit refusal of follow-up, or inability to visit the hospital for informed consent signing and DXA examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic performance of the DeepBMD model; | — |
Secondary
| Measure | Time frame |
|---|---|
| Computational success rate of DeepBMD;Patient recall rate; | — |
Countries
China
Contacts
Public ContactYang Fan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed