Lumbar disc herniation
Conditions
Interventions
Early treatment group (4 weeks - 6 weeks),:None
Delayed treatment group (6 weeks - 6 months):None
Sponsors
Zhabei Center Hospital of JingAn District of Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65, male or female; 2. Presenting with clear symptoms of nerve root compression, with a NRS score of >=7; 3. Diagnosed with single-level LDH (L4/5 or L5/S1) through imaging examination; 4. Scheduled for lumbar posterior UBE surgery; 5. Signed the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Patients with symptoms lasting for more than 6 months, or with a history of previous lumbar surgery or recurrent lumbar disc herniation (LDH); 2. Patients with chronic axial low back pain and lumbar instability; 3. Patients with severe cardiopulmonary, hepatic, renal, and renal dysfunction, who are unable to tolerate surgery; 4. Patients with acute moderate or severe paralysis (MRC<=3/5, foot drop), or patients with cauda equina syndrome; 5. Patients with spinal tumors, infections, deformities, ankylosing spondylitis, coagulation dysfunction, or hematological diseases; 6. Pregnant or lactating women; 7. Patients with mental illness; 8. Patients with diabetic neuropathy or other peripheral neuropathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of root symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological function;Quality of life; | — |
Countries
China
Contacts
Public ContactWang Zhiqing
Zhabei Center Hospital of JingAn District of Shanghai
Outcome results
None listed