Helicobacter pylori infection
Conditions
Interventions
Observation group:None
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Historical cohort population: Derived from the national epidemiological survey on digestive system diseases conducted by the research team from 2015 to 2018, those who completed the ¹³C breath test and were aged 18 years or above were included; individuals with negative baseline Helicobacter pylori status or those with positive baseline status and subsequent eradication treatment were included in the analysis. 2.Multicenter physical examination population: Derived from the archived records of the physical examination departments of multiple medical institutions, those aged 18 years or above with complete data and including ¹³C breath test results were included; those with >=2 records of ¹³C breath tests in the past 10 years were given priority for inclusion. 3.Population associated with the Beijing Health Commission platform: Derived from the national health information platform of Beijing, those aged 18 years or above within the platform and with previous medical visit records were included; outpatient medical records, laboratory test results, and cross-institutional visit trajectories were obtained through platform association for improving co-morbidity diagnosis and long-term outcome tracking.
Exclusion criteria
Exclusion criteria: 1.Patients with incomplete medical visit information;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inter-group differences in incidence risk of metabolic, cardiovascular, hematological and mental chronic diseases under three Hp statuses; | — |
Secondary
| Measure | Time frame |
|---|---|
| Independent impact of Hp drug resistance on incident risk of hypertension, coronary heart disease and stroke;Independent impact of Hp drug resistance on incident risk of type 2 diabetes mellitus and dyslipidemia;Independent impact of Helicobacter pylori drug resistance on incident risk of iron deficiency anemia and immune thrombocytopenia (ITP);Protective effect of successful Hp eradication on incidence risk of multiple systemic chronic diseases including metabolic, cardiovascular, hematological and mental diseases;Independent impact of Helicobacter pylori drug resistance on incident risk of anxiety disorder and depressive disorder;The difference in the incidence of gastric mucosal intestinal metaplasia/ atypical hyperplasia; | — |
Countries
China
Contacts
Public ContactYang Hong
Peking Union Medical College Hospital
Outcome results
None listed