Skip to content

A real-world observational study on the efficacy of laser-assisted photodynamic therapy in the treatment of oral leukoplakia

A real-world observational study on the efficacy of laser-assisted photodynamic therapy in the treatment of oral leukoplakia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600129089
Enrollment
Unknown
Registered
2026-07-30
Start date
2025-09-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral leukoplakia

Interventions

Observation group:None

Sponsors

West China Hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients clinically and histopathologically diagnosed with oral leukoplakia 2. Aged 18 years or older 3. Willing to participate in the study and sign an informed consent form 4. Patients who, based on routine initial examinations (such as complete blood count, liver and kidney function tests, fasting blood glucose, blood lipids, and coagulation function), are determined to be in a general condition suitable for the proposed treatment plan

Exclusion criteria

Exclusion criteria: 1.Patients with unassessable therapeutic efficacy resulting from untimely follow-up 2. Patients with missing baseline information 3. Pregnant or lactating women 4.Patients with porphyria, porphyrin allergy, photosensitivity, allergy to topical aminolevulinic acid hydrochloride powder, allergy to local anesthetics, or coagulation disorders 5. Patients with other severe systemic diseases

Design outcomes

Primary

MeasureTime frame
Malignant transformation event;Recurrence rate;

Secondary

MeasureTime frame
Lesion area before treatment;Lesion area after treatment;Number of treatment sessions;

Countries

China

Contacts

Public ContactHongxia Dan

West China Hospital of Stomatology, Sichuan University

hxdan@foxmail.com+86 138 8079 6101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026