Postoperative Gastrointestinal Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meets the indications for elective surgery under general anesthesia laparoscopic radical gastrectomy for gastric cancer or colorectal cancer; 2. Age: 18 to 85 years old (inclusive), with complete cognitive function and symptom description ability, and good compliance; 3. Confirmed by histopathology as gastric cancer or colorectal cancer, with TNM stage b-?c and meeting the criteria for surgical resection assessment; 4. No chronic metabolic diseases that affect autonomic nerve function and cardiovascular regulation (such as uncontrolled hypertension and diabetes); 5. National Society of Anesthesiologists (ASA) classification <= Grade III; 6. Preoperative gastrointestinal motility assessment showed no organic or functional abnormalities. 7. Voluntarily participate in the research and sign the informed consent document reviewed by the ethics committee.
Exclusion criteria
Exclusion criteria: 1. There is tumor recurrence or distant metastatic lesions; 2. Those who have continuously used central nervous system inhibitors or psychoactive substances within 30 days before the operation, or have a history of chronic insomnia; 3. There is a history of language communication disorders or organic diseases of the neuropsychiatric system; 4. Combined with severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction or moderate malnutrition status (albumin 10% within 6 months); 5. Implantable electronic medical devices in the body (such as pacemakers, nerve stimulators, etc.) or metal prostheses; 6. Suspected or confirmed history of alcohol or drug abuse. 7. Other lesions that, based on the researcher's judgment, may reduce the possibility of enrollment or complicate enrollment, such as the working environment Frequent changes and other situations that can easily lead to loss of follow-up. 8. Participate in other clinical intervention studies simultaneously.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first postoperative flatus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first postoperative defecation;Bowel sound recovery time;Time to tolerance of oral diet;Heart rate variability parameters;Length of postoperative hospital stay;Pain assessment;Sleep quality;Inflammatory markers;Safety indicators; | — |
Countries
China
Contacts
Affiliated Hospital of Nanjing University of Chinese Medicine(Jiangsu Province Hospital of Chinese Medicine)