Benign and malignant breast tumours
Conditions
Interventions
Control group:Receive sham stimulation, with the stimulation process and time schedule being the same as those of the intervention group, but without generating effective magnetic stimulation.
Intervention group:First, perform iTBS stimulation on the left DLPFC. After approximately 20 minutes, conduct another iTBS stimulation, with a total of 2 stimulations.
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18–65 years; 2.ASA classification I–III; 3.Proposed elective breast-conserving surgery for breast cancer or benign lumpectomy of breast; 4.Patients with a score of >=12 on the Amsterdam Preoperative Anxiety and Information Scale (APAIS); 5.Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Contraindications for rTMS (such as intracranial metal implants, pacemakers, personal or family history of epilepsy); 2.Long-term use of opioids, sedative medications (within three months), or a diagnosis of chronic pain syndrome; 3.Severe mental or cognitive dysfunction that prevents them from communicating or cooperating with the assessment; 4.History of drug or alcohol abuse; 5.Pre-operative pre-existing neurological deficits; 6.Pregnant or breastfeeding women; 7.Any other circumstances that the researcher considers unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting and movement pain scores;Record of the use of postoperative analgesic drugs;Adverse events / Serious adverse events; | — |
Countries
China
Contacts
Public ContactHu Xin
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed