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Practical Approach to Emergency Care for Air Embolism Complicating Surgery in a Patient with Choroidal Melanoma

Practical Approach to Emergency Care for Air Embolism Complicating Surgery in a Patient with Choroidal Melanoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128986
Enrollment
Unknown
Registered
2026-07-29
Start date
2026-07-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Vein Air Embolism (OVAE)

Interventions

Control group:None

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Case Group: (1) Underwent posterior approach vitrectomy combined with air-fluid exchange at our hospital. (2) Clinically diagnosed with acute air embolism during surgery (based on the diagnostic criteria in this case: sudden drop in PetCO2, difficult-to-correct hypotension, newly appeared ECG changes, and confirmation of intracardiac gas bubbles via echocardiography). (3) Complete medical records. 2. Control Group: (1) Underwent posterior approach vitrectomy combined with air-fluid exchange at our hospital. (2) Clearly did not experience air embolism during or after surgery. (3) Successfully matched with the case group patients in age, gender, and primary diagnosis.

Exclusion criteria

Exclusion criteria: 1. Known heart conditions with right-to-left shunting before surgery (like patent foramen ovale or atrial septal defect). 2. Severe respiratory and circulatory failure before surgery that requires high doses of vasoactive drugs to maintain. 3. Key data missing from medical records (like intraoperative vital signs, surgery notes, blood gas analysis results, etc.).

Design outcomes

Primary

MeasureTime frame
End-tidal carbon dioxide(PetCO2);Pulse oximetry(SpO2) ;The extent of thedecrease in blood pressure;Success rate of air embolismrescue procedures;Time takento restore vital signs within 35;

Countries

China

Contacts

Public ContactGuo Yao

The First Affiliated Hospital of Nanchang University

1837000581@qq.com+86 791 8869 8325

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026