Patients with a confirmed diagnosis who require laparoscopic radical resection for gastrointestinal tumors
Conditions
Interventions
Control Group:Bupivacaine liposome for transversus abdominis plane (TAP) block
experimental group:Ropivacaine combined with dexamethasone for transversus abdominis plane (TAP) block
Sponsors
The First Affiliated Hospital,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients with a clear diagnosis who require laparoscopic radical resection for gastrointestinal tumors; 2.Aged 18-70 years old; BMI 18-28 kg/m2; 3.ASA classification of I-III; 4.The patient is able to understand the written informed consent form and has the willingness to sign the document.
Exclusion criteria
Exclusion criteria: 1.Patients with previous severe diseases of vital organs such as heart, lungs, and kidneys, metabolic diseases, and chronic pain; 2.Patients with a history of abuse of alcohol, narcotics, or analgesic drugs; 3.Having mental illness or cognitive impairment, unable to communicate normally; 4.Allergic to relevant anesthetic drugs; 5.Use of antiemetic, analgesic, sedative, and anti-itch medications within 24 hours before surgery; 6.Patients with bronchial asthma who are allergic to non-steroidal anti-inflammatory drugs (NSAIDs) or ropivacaine; 7.Patients with a history of chronic pain who have been treated with long-term analgesics (NSAIDs, opioids) or steroids, as well as those with sensory abnormalities or peripheral neuropathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine milligram equivalents (MME) taken orally within 48 hours after surgery.; | — |
Countries
China
Contacts
Public ContactAn Ke
The First Affiliated Hospital,Sun Yat-sen University
Outcome results
None listed