Early Gastric Cancer
Conditions
Interventions
Magnifying Endoscopy Group:Participants undergo magnifying endoscopy, with lesion assessment and targeted biopsy decisions guided by the MESDA-G algorithm.
4K Ultra-High-Definition Non-Magnifying Endoscopy Group:Participants undergo 4K ultra-high-definition non-magnifying endoscopy, with lesion screening and targeted biopsy decisions guided by the SPEG-H
Sponsors
The Seventh Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Adults aged 40–75 years who are scheduled to undergo upper gastrointestinal endoscopy for either clinical indications or screening purposes; 2.Willingness to participate in the study, with written informed consent obtained prior to the examination.
Exclusion criteria
Exclusion criteria: 1.Individuals undergoing any therapeutic gastroscopic procedures, including emergency endoscopy; 2.Known, untreated gastric cancer or precancerous lesions; 3.Other malignant tumors of the upper gastrointestinal tract; 4.Individuals who have undergone partial or total gastrectomy; 5.Individuals with severe underlying diseases, such as cardiac or pulmonary insufficiency, cerebrovascular disease, or other conditions precluding careful endoscopic observation; 6.Individuals with gastric retention, esophageal strictures, or other conditions that prevent thorough observation of the stomach; 7.Individuals who refuse to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive predictive value of biopsy for early gastric cancer screening using ultra-high definition non-magnifying endoscopy versus magnifying endoscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection rate of ultra-high definition non-magnifying endoscopy versus magnifying endoscopy for early gastric cancer patients;Procedure time of ultra-high definition non-magnifying endoscopy versus magnifying endoscopy for screening early gastric cancer; Detection rate of ultra-high definition non-magnifying endoscopy versus magnifying endoscopy for early esophageal cancer;Positive predictive value of targeted biopsy for early esophageal cancer using ultra-high definition non-magnifying endoscopy versus magnifying endoscopy; | — |
Countries
China
Contacts
Public ContactPeng Jin
The Seventh Medical Center of Chinese PLA General Hospital
Outcome results
None listed