Osteoporosis
Conditions
Interventions
Standard Care Group:Anti-osteoporotic Treatment
LLM-Assisted Intervention Group (FloraBone Group):Anti-osteoporotic treatment combined with personalized large language model–assisted intervention
Sponsors
The First Affiliated Hospital Of USTC; Anhui Provincal Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Aged 50-75 years; 2.Meeting the diagnostic criteria for osteoporosis; 3.Having a junior high school education or above, with basic reading, writing, and comprehension abilities, and being able to use a smartphone proficiently; 4.Voluntarily participating in the study and signing the informed consent form, being able to cooperate with follow-up visits and relevant indicator assessment, and agreeing to comply with the study procedures.
Exclusion criteria
Exclusion criteria: 1.Severe skeletal deformities, such as scoliosis, or a history of traumatic fracture within the past year; 2.Comorbid hyperparathyroidism, severe hepatic or renal dysfunction, malignant tumors, autoimmune diseases, or severe infectious diseases; 3.Long-term use of medications affecting bone metabolism, such as high-dose glucocorticoids or antiepileptic drugs, and inability to discontinue such medications; 4.Incomplete baseline data, cognitive impairment, psychiatric disorders, or inability to cooperate with the study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lumbar spine or hip BMD;Incidence of osteoporotic fractures; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone turnover markers and serum electrolytes;Participant adherence to and satisfaction with the FloraBone system;Participant intervention adherence; | — |
Countries
China
Contacts
Public ContactWang Wei
The First Affiliated Hospital Of USTC; Anhui Provincal Hospital
Outcome results
None listed