Dental caries? Periodontal disease
Conditions
Interventions
Control group:Use of a negative control toothpaste (KuaiKouli JinHouJian Specialized Toothpaste without active ingredients).
Experimental group:Use of KuaiKouli JinHouJian Specialized Toothpaste containing active ingredients.
Sponsors
Stomatological Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Non-allergic constitution, in good general health, without serious systemic diseases, and having at least 20 natural teeth available for examination. 2. Aged between 18 and 70 years, with no restriction on sex; female participants must not be pregnant or breastfeeding and must have no plans for pregnancy within the past six months. 3. At the screening visit, the participant has a dental plaque index score of = 1.5. 4. Willing to refrain from any form of oral cleaning for 8–16 hours prior to each study visit, to consume no food or beverages other than plain water on the morning of each visit, and to stop drinking water at least 30 minutes before the visit. 5. Willing to avoid the use of oral care products containing antimicrobial agents for the chemical treatment of gingivitis during the study period, including but not limited to products containing amine fluoride, chlorhexidine, stannous fluoride, essential oils, or cetylpyridinium chloride. 6. Non-smokers and non-users of other nicotine-containing products. 7. Not concurrently participating in any other similar clinical trials or studies; 8. Has signed the informed consent form and is able to complete the clinical trial as required.
Exclusion criteria
Exclusion criteria: 1. History of allergy to any ingredients of the investigational toothpaste. 2. Use of medications that may affect the study outcomes, such as antibiotics, within one month prior to participation in the study. 3. Presence of open dental caries or oral mucosal lesions. 4. Presence of severe periodontitis, defined as having probing pocket depths greater than 5 mm in more than one tooth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plaque Index,PI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral soft and hard tissue examination and assessment of adverse events.; | — |
Countries
China
Contacts
Public ContactJianbo Li
Stomatological Hospital of Southern Medical University
Outcome results
None listed