mediastinal metastasis of lung cancer
Conditions
Interventions
Experimental group:Following the completion of EBUS-TBNA, EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TBMCB) will be performed.
Control group:Endobronchial ultrasound–guided transbronchial needle aspiration (EBUS-TBNA) will be performed.
Sponsors
The Second Affiliated Hospital of Third Military Medical University (Xinqiao Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 80 years >= Age >= 18 years; 2. Presence of at least one mediastinal lesion (short-axis diameter =10 mm) confirmed by thin-slice chest CT; 3. For clinically suspected or confirmed lung cancer requiring mediastinal staging, biopsy is necessary to determine the etiology or pathological subtype; 4. Patients must have completed all required preoperative laboratory tests and necessary examinations (e.g., cardiac ultrasound, CTA) to rule out contraindications; 5. Patients are informed and capable of providing written informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of severe cardiopulmonary disease, coagulation disorders, massive hemoptysis, poor tolerance to anesthesia, or other contraindications related to bronchoscopy; 2. Intraoperative endobronchial ultrasound exploration of the lesion failed to detect the target lesion despite > 20 minutes of attempts; 3. Lesions identified as abscesses or cysts; 4. Presence of mental illness, severe neurosis, or other conditions that preclude the provision of informed consent; 5. Patients who have participated in other clinical trials within 3 months; 6. Any other conditions considered to be inappropriate to be involved in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic yield for lung cancer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy;Sample adequacy;Suitability for molecular assays;Duration of bronchoscopic procedure;Incidence of procedure-related adverse events;Sample size; | — |
Countries
China
Contacts
Public ContactFan Ye
The Second Affiliated Hospital of Third Military Medical University (Xinqiao Hospital)
Outcome results
None listed