late-onset Alzheimers disease, mild cognitive impairment, and other cognitive disorders
Conditions
Interventions
Hospital-based older adult screening group:None
Sponsors
Hangzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Participants aged 60 years or older who undergo health examinations in the hospital. 2.Participants who voluntarily agree to participate and provide written informed consent. 3.Participants who are able to complete basic information collection and cognitive screening and who agree to the use of 1–3 mL of residual EDTA-anticoagulated blood remaining after routine complete blood count testing. 4.For participants with suspected cognitive decline who are unable to fully understand the informed consent information, written informed consent shall be provided by a legal guardian or legally authorized representative, while the participant’s own willingness and assent shall be respected whenever possible.
Exclusion criteria
Exclusion criteria: 1.Individuals who refuse to participate or refuse to provide informed consent. 2.Individuals who are unable to complete the screening due to severe physical illness, acute infection, severe mental disorder, or other conditions. 3.Participants without a residual blood sample from routine complete blood count testing that meets the quality requirements of the study. 4.Individuals considered unsuitable for participation by the investigators. 5.Participants who request withdrawal during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of participants meeting assay-specific decision thresholds for AD-related peripheral blood biomarkers; | — |
Secondary
| Measure | Time frame |
|---|---|
| Abnormal rate of cognitive screening; | — |
Countries
China
Contacts
Public ContactWang Ying
Hangzhou First People's Hospital
Outcome results
None listed