Menopausal symptoms
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.women aged 40–60 years; 2.Proximally, menstrual cycle length variation of =7 days, recurring within 10 menstrual cycles, or amenorrhea for more than one year; 3.complete clinical data, including menopause-related symptom scores, body composition measurements, and hormone level assessments;
Exclusion criteria
Exclusion criteria: 1.previously undergone oophorectomy (ovariectomy) or hysterectomy; 2.Use of medications affecting hormone levels or bone metabolism within the past three months, including estrogen/progestin preparations, glucocorticoids, thyroid hormone replacement therapy, bisphosphonates, selective estrogen receptor modulators. etc; 3.Use of any medication for the treatment of menopause-related symptoms within the past two months; 4.Patients diagnosed with diseases affecting endocrine function or bone metabolism, such as parathyroid disorders, hyperthyroidism or hypothyroidism, Cushing's syndrome, malabsorption syndrome, etc; 5.Presence of malignant tumors; 6.Pregnancy or lactation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| KMI score;Body composition parameters (weight, waist-to-hip ratio, body fat percentage, visceral fat grade, and muscle mass(Index);Sex hormone levels: follicle-stimulating hormone (FSH), estradiol (E2), and anti-Müllerian hormone (AMH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone mineral density (lumbar spine, right hip); | — |
Countries
China
Contacts
International Peace Maternity and Child Health Hospital of China Welfare Institute