Lung cancer
Conditions
Interventions
Experimental group:Tubeless technique + tunnel-style en bloc functional mediastinal lymph node dissection.
Normal group:Tubeless technique + conventional mediastinal lymph node dissection.
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Sign the informed consent form; 2. The pathological diagnosis indicates a malignant tumor in the lung, and a lung lobe resection is required; 3. Use laryngeal mask for ventilation; 4. Age (18 - 70 years old); 5. ECOG score 70%.
Exclusion criteria
Exclusion criteria: 1. Presence of chronic cough symptoms before surgery; 2. Postnasal drip syndrome, bronchial asthma, or oral use of angiotensin-converting enzyme inhibitors; 3. Patients who refuse the surgical and/or anesthesia plan; 4. Coagulopathy, hypoxemia (PaO2 50 mmHg), or an increased risk of regurgitation preoperatively or associated with gastroesophageal reflux disease (fasting < 6 hours); neurological disorders; 5. Severe acute pulmonary infection or pulmonary tuberculosis; 6. Relative contraindications: upper respiratory tract secretions or persistent cough, spinal deformity, or cerebral edema (if thoracic epidural anesthesia is used); 7. History of ipsilateral surgery and other conditions that may lead to extensive pleural adhesions; 8. Phrenic nerve paralysis on the non-operative side should be considered a contraindication to VATS; 9. Significant history of heart disease; 10. Allergy to local anesthesia; 11. Any contraindication to local anesthesia techniques; 12. Difficult airway management; 13. Preoperative pleural effusion; emphysema; residual bullae.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic cough within 3 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The LCQ-MC score within 3 months after the operation; | — |
Countries
China
Contacts
Public ContactChen Shuchen
Fujian Medical University Union Hospital
Outcome results
None listed