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Pregnancy-Associated aHUS Complicated by Renal Cortical Necrosis Treated with Eculizumab: A Case Report

Pregnancy-Associated Atypical Hemolytic Uremic Syndrome Complicated by Renal Cortical Necrosis Treated with Eculizumab: A Case Report

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128903
Enrollment
Unknown
Registered
2026-07-28
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy-Associated Atypical Hemolytic Uremic Syndrome

Interventions

Case Series:None

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Adult pregnant female patients; 2.Visited the Department of Nephrology, Shenzhen Second People's Hospital between October 2024 and June 2025; 3.Diagnosed with atypical hemolytic uremic syndrome (aHUS) according to the 2023 British Society for Haematology (BSH) guideline on "Thrombotic Thrombocytopenic Purpura and Other Thrombotic Microangiopathies"; 4.Treated with eculizumab; 5.Complete medical records.

Exclusion criteria

Exclusion criteria: Patients deemed unsuitable for participation in this study by the investigator.

Design outcomes

Primary

MeasureTime frame
Renal function recovery after eculizumab therapy for acute kidney injury;—

Countries

China

Contacts

Public ContactYi Xu

Shenzhen Second People's Hospital

xuyi20001234@163.com+86 755 83366388

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026