Severe Fever with Thrombocytopenia Syndrome
Conditions
Sponsors
The first affiliated hospital of anhui medical university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria specified in the Diagnosis and Treatment Protocol for Severe Fever with Thrombocytopenia Syndrome, with positive laboratory test results for SFTSV RNA. 2.Aged 18 or above, no gender restrictions; 3.Hospital stay >= 4 days, and 30-day prognostic follow-up can be completed; 4.The patient or legal representative shall sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Unable to cooperate with data collection, suffering from mental disorders or communication disorders; 2.Other circumstances judged by researchers as ineligible for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Secondary infection rate within 30 days;28-day mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Broad-spectrum antibiotic use rate;ICU admission rate;Blood transfusion rate;Antibiotic-related adverse reaction rate;Platelet count dynamics;Duration of antibiotic use;30-day readmission rate;Adverse event (AE) rate;Abnormal rate of liver, myocardial and inflammatory markers;Incidence of consciousness disturbance;Serious adverse event (SAE) rate;Mean length of hospital stay;Rate of dysbiosis/secondary fungal infection;Antibiotic combination therapy rate;Bleeding event rate;Proportion of abnormal GCS scores;Mechanical ventilation rate; | — |
Countries
China
Contacts
Public ContactHu Lifen
The first affiliated hospital of anhui medical university
Outcome results
None listed