Thermal burns
Conditions
Interventions
oliceridine group(Group O):Oliceridine intravenous iniection
Sufentanil Group (Gruop S):Sufentanil intravenous iniection
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age 18 to 70 years; 2.ASA physical status classification I to III; 3.Patients with moderate to severe burns (deep second-degree to third-degree burns, TBSA 10% to 40%) scheduled for elective escharotomy and skin grafting; 4.Willingness to participate in the study and signing of informed consent;
Exclusion criteria
Exclusion criteria: 1. Individuals with allergies to oliceridine or other opioid medications; 2. Patients with severe cardiovascular or cerebrovascular diseases, respiratory disorders, or impaired liver/kidney function; 3. Individuals with psychiatric disorders or cognitive impairments; 4. Pregnant or lactating women; 5. Patients who have used opioid medications for more than 7 days prior to surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 15-Item Postoperative Recovery Quality Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of effective bolus doses, total bolus doses, and use of rescue analgesia;Adverse Reactions;NRS;Ramsay; | — |
Countries
China
Contacts
Public ContactHailang Wang
Affiliated Hospital of Jiangnan University
Outcome results
None listed