Stroke, fatigue, post-stroke fatigue
Conditions
Interventions
Health group:None
Non-post stroke fatigue group:None
Post stroke fatigue group:None
Sponsors
Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for healthy subjects: (1). Age between 18 and 75 years, regardless of gender; (2). Vital signs within normal range, and willing to provide informed consent to participate in the study. 2. Inclusion criteria for stroke patients: (1). Age 18–75 years, regardless of gender; (2). Stroke diagnosis: all cases meet the diagnostic criteria for stroke established by the National Society of Cerebrovascular Diseases; (3). Sitting balance score of at least level 3; (4). Stable vital signs, and informed consent to participate in the study; (5). Fatigue-free stroke group: FSS score = 4 points.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for healthy subjects: (1). Have contraindications for exercise (cardiovascular diseases, metabolic and endocrine disorders, neurological and musculoskeletal disorders, recent surgery/trauma, etc.), or have other underlying diseases affecting fatigue; (2). Have a history of neurological or psychiatric disorders; (3). Be color-blind/has color vision deficiency, or have abnormal vision or corrected vision; (4). Have severe sleep deprivation, be a long-term smoker, alcoholic, or drug abuser; (5). Pregnant or breastfeeding; (6). Have metal implants in the body. 2. Exclusion criteria for stroke: (1). Those with hearing comprehension or severe cognitive impairments that affect their ability to understand the research process or provide accurate feedback; (2). Those with concurrent malignant tumors, severe mental illnesses, bleeding disorders, or other major diseases; (3). Those with other serious physical conditions that affect fatigue, such as severe cardiovascular diseases, chronic obstructive pulmonary diseases, or other major diseases that may affect an individual's sense of fatigue; (4). Those with severe joint injuries, neurological muscle diseases, uncontrolled hypertension, recent surgery/trauma, etc.; (5). Those with severe sleep deprivation, in the acute fatigue period; (6). Those with color blindness/achromatopsia, abnormal vision or corrected vision.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue numeric rating scale, Rating of Perceived Exertion 6-20; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure, heart rate, electrocardiogram;Surface electromyography, near-infrared brain functional imaging / functional magnetic resonance imaging, endurance time, number of completed cycles, reaction time, accuracy rate, heart rate variabili; | — |
Countries
China
Contacts
Public ContactYang Yun
Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
Outcome results
None listed