Elevated blood lipid margin
Conditions
Interventions
Test Article Group 2:Participants will replace their household cooking oil with the test article (diacylglycerol edible oil containing 60% DAG) at a daily dose of 30 mL for 12 consecutive weeks.
Test Article Group 1:Participants will replace their household cooking oil with the test article (diacylglycerol edible oil containing 40% DAG) at a daily dose of 30 mL for 12 consecutive weeks.
Control Group:Participants will replace their daily household cooking oil with the control oil (rapeseed oil) at a fixed dose of 30 mL per day for 12 consecutive weeks.
Sponsors
Suzhou Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years (including boundary values), both genders. 2. BMI >=30 kg/m^2, or total body fat percentage >25% for males and >30% for females. 3. Dyslipidemia: 5.18 mmol/L <= serum total cholesterol <=6.21 mmol/L, or 1.70 mmol/L <= serum triglycerides <=2.25 mmol/L. 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women, as well as those who have pregnancy plans during the trial period; 2. People with allergic constitutions or those allergic to diglycerol; 3. Patients with severe diseases of the heart, liver, kidneys and hematopoietic system, as well as those with mental illness; 4. Patients with hyperlipidemia; 5. Those who have taken lipid-lowering drugs in the past two weeks and whose judgment of the results has been affected: Lipid-lowering includes: Statins (such as atorvastatin, rosuvastatin) (2) Cholesterol absorption inhibitors (such as ezetimibe) (3) Fibrate drugs (such as fenofibrate, benzafifibrate) (4) Other drugs that the researcher determines may affect the research results; 6. The researcher believes that the compliance is poor, or the researcher believes that the subject has any other circumstances that make it unsuitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood lipid (LDL-C);Body fat content; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood lipid;weight;renal function;Adverse events and serious adverse events;Body Mass Index;Blood routine test;72-hour dietary questionnaire survey;Hip circumference;Waist circumference;Exercise Status Questionnaire Survey;Liver function;Subcutaneous fat thickness; | — |
Countries
China
Contacts
Public ContactZhang Jianwei
Suzhou Municipal Hospital
Outcome results
None listed