Diabetic Kidney Disease (DKD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. A confirmed diagnosis of type 2 diabetes mellitus with a disease duration of >= 5 years; 2. Persistent normoalbuminuria at baseline (UACR = 90 mL/min/1.73m² with documented evidence of an annual eGFR decline rate > 5 mL/min/1.73m², which should be validated by two eGFR measurements separated by a minimum of 12 months; 4. Presence of at least one DKD high-risk factor, including HbA1c > 7.5%, a history of hypertension, or any grade of diabetic retinopathy.
Exclusion criteria
Exclusion criteria: 1. Known or suspected non-diabetic renal diseases; 2. A diagnosis of type 1 diabetes mellitus; 3. Severe ocular diseases (other than diabetic retinopathy) that may substantially affect fundus imaging quality; 4. Failure to provide informed consent or complete follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary Albumin/Creatinine Ratio, UACR; | — |
Secondary
| Measure | Time frame |
|---|---|
| estimated Glomerular Filtration Rate, eGFR ; | — |
Countries
China
Contacts
Beijing Chaoyang Hospital, Capital Medical University