Skip to content

Analysis of the Development Trajectory and Influencing Factors of Cognitive Function in Elderly Patients with Visual impairment

Analysis of the Development Trajectory and Influencing Factors of Cognitive Function in Elderly Patients with Visual impairment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128853
Enrollment
Unknown
Registered
2026-07-27
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Visual impairment

Interventions

Visually Impaired Group:None

Sponsors

Tianjin Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 60 years old; 2. Confirmed by an ophthalmologist to have moderate or above visual impairment (based on comprehensive visual indicators such as best corrected visual acuity, contrast sensitivity or visual field defects); 3. Able to understand and sign the informed consent form, and agree to participate in the follow-up study; 4. Possesses normal comprehension, cognition and communication skills and voluntarily participates in this study with informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe hearing impairment or aphasia, making verbal cognitive assessment impossible to complete; 2. In a state of acute delirium, or suffering from severe mental illnesses (such as schizophrenia and bipolar disorder) that interfere with cognitive assessment; 3. Advanced malignant tumors, or a life expectancy of less than 6 months as assessed by a clinician; 4. Definite diagnosis of dementia (e.g., Alzheimer's disease, vascular dementia) or moderate-to-severe cognitive impairment (mild cognitive impairment should be carefully excluded based on clinical history and neuroimaging evidence); 5. History of major cerebrovascular events (e.g., cerebral infarction, intracerebral hemorrhage) with significant neurological sequelae; 6. Cognitive or visual symptoms attributable to other neurodegenerative diseases (e.g., Parkinson's disease).

Design outcomes

Primary

MeasureTime frame
Trajectory of cognitive function changes over time (based on MoCA-Basic and ACE-III scores); differences among trajectory categories; predictive effects of visual function and psychosocial variables o;

Secondary

MeasureTime frame
Mediating/moderating effects of depression level and social support in the visual-cognitive relationship; changing trends of activities of daily living (ADL, IADL); longitudinal changes in physical ac;

Countries

China

Contacts

Public ContactZhao Rui

Tianjin Eye Hospital

zhaorui198802@163.com+86 22 23187214

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026