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Correlation Between Frontalis EMG in BIS Monitoring and Adductor Pollicis TOF Monitoring for Neuromuscular Blockade During General Anesthesia

Correlation Between Frontalis EMG in BIS Monitoring and Adductor Pollicis TOF Monitoring for Neuromuscular Blockade During General Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128831
Enrollment
Unknown
Registered
2026-07-27
Start date
2026-07-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

BIS frontalis EMG group:None
Adductor Pollicis TOF Group:None

Sponsors

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective surgery under general anesthesia; 2. ASA physical status classification Grade ? to ?; 3.Aged between 18 and 85 years inclusive; 4. Expected operative duration <=3 hours; 5. No administration of drugs affecting neuromuscular transmission preoperatively; 6. Signed informed consent obtained.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating females; 2.Obesity (BMI > 30 kg/m^2); 3. Severe hepatic or renal dysfunction, electrolyte imbalance; 4. Skin lesions or nerve injury on the face or hands; 5.Neuromuscular diseases; 6. Long-term use of glucocorticoids or muscle relaxants; 7. Family history of malignant hyperthermia; 8. Hypersensitivity to propofol, sufentanil, or cisatracurium besylate; 9. Any other conditions deemed inappropriate by the investigator for participation in this trial.

Design outcomes

Primary

MeasureTime frame
TOF values ;BIS-derived frontalis EMG values;Onset time of neuromuscular blocking agent;Recovery time of neuromuscular blocking agent;

Secondary

MeasureTime frame
BIS value;Complications of residual neuromuscular blockade after extubation;Incidence rate of postoperative adverse facial skin reactions (redness, itching, etc.);Electrode detachment rate;Signal interference incidence rate;

Countries

China

Contacts

Public ContactShangguan Wangning

Wenzhou Medical University Affiliated Stomatological Hospital

sgwning@163.com+86 135 8763 7891

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026